Lactoferrin

An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the TYPE III SECRETION SYSTEM used by bacteria to export virulence proteins for host cell invasion.

Also Known As:

Lactotransferrin

Pharmalogical Action Categories:

Anti-Infective Agents

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        Lactoferrin: 2659
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        Lactoferrin: 2659
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Lactoferrin: 2659
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Lactoferrin: 2659
  - Carrier Proteins: 12999
    - Iron-Binding Proteins: 172
      - Transferrins: 33
        Lactoferrin: 2659
  - Globulins: 3062
    - Lactoglobulins: 372
      - Lactoferrin: 2659
  - Dietary Proteins: 2387
    - Dietary Animal Proteins: 18
      - Milk Proteins: 847
        Whey Proteins: 703
        Lactoglobulins: 372
        Lactoferrin: 2659
  - Metalloproteins: 164
    - Iron-Binding Proteins: 172
      - Transferrins: 33
        Lactoferrin: 2659

Antonio Aguila Selected Research

Antonio Aguila Research Topics

Disease

Drug/Important Bio-Agent (IBA)